Henry C. Bradford built the house in 1819, the same year Alabama became a state. It is a fine example of Federal period domestic architecture. Architectural details such as the roof cornice medallions, the frieze below the front eaves and the leaded glass fanlight over the front door are all typical of the period. Dr. William Weeden purchased the property in 1845 and except for the time during the Civil War when Union Forces requisitioned it for use, it remained in the family until it was sold in 1956.
Now owned by the City of Huntsville, it is leased by the Twickenham Historic Preservation District Association and maintained as a 19th century house museum. The furnishings are based on Dr. Weeden’s inventories and there are a number of original Weeden pieces on display. The detached kitchen was reconstructed from the 1935 HABS architectural drawings. The house is open for tours, Tuesday-Saturday, 10 AM – 3 PM and is available for weddings, receptions, teas and parties.